Lipitor


> Category: Pharmaceutical
> Total sales: $141 billion
> Parent company: Pfizer

Pfizer’s Lipitor is prescribed to lower LDL (or bad) cholesterol — high levels of bad cholesterol increase the risk of heart disease. Lipitor is classified as a statin, a class of drug used to reduce the risk of heart-related ailments. However, Lipitor sales have plummeted in recent years after its U.S. patent expired in 2011. Lipitor has lost patent protection in other major markets since. In 2013, Lipitor sales totaled $2.3 billion, down from $9.6 billion in 2011 according to Pfizer’s 2013 annual report. Still, since its introduction in 1997, no other drug came close to Lipitor’s commercial success. The closest competitor for all time sales is Plavix, which had slightly more than half of Lipitor’s lifetime revenue, according to Forbes.

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